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Malaria is a mosquito-borne infectious disease that affects vertebrates. [6] [7] [3] Human malaria causes symptoms that typically include fever, fatigue, vomiting, and headaches. [1] [8] In severe cases, it can cause jaundice, seizures, coma, or death. [1] [9] Symptoms usually begin 10 to 15 days after being bitten by an infected Anopheles ...
Malaria researchers have won multiple Nobel Prizes for their achievements, although the disease continues to afflict some 200 million patients each year, killing more than 600,000. Malaria was the most important health hazard encountered by U.S. troops in the South Pacific during World War II, where about 500,000 men were infected. [6]
Plasmodium falciparum. Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans. [ 2] The parasite is transmitted through the bite of a female Anopheles mosquito and causes the disease's most dangerous form, falciparum malaria.
Malaria prophylaxis. Malaria prophylaxis is the preventive treatment of malaria. Several malaria vaccines are under development. For pregnant women who are living in malaria endemic areas, routine malaria chemoprevention is recommended. It improves anemia and parasite level in the blood for the pregnant women and the birthweight in their infants.
Plasmodium rodhaini Brumpt, 1939. Plasmodium malariae is a parasitic protozoan that causes malaria in humans. It is one of several species of Plasmodium parasites that infect other organisms as pathogens, also including Plasmodium falciparum and Plasmodium vivax, responsible for most malarial infection.
Antimalarial medication. Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women. [ 1] As of 2018, modern treatments, including ...
Human genetic resistance to malaria refers to inherited changes in the DNA of humans which increase resistance to malaria and result in increased survival of individuals with those genetic changes. The existence of these genotypes is likely due to evolutionary pressure exerted by parasites of the genus Plasmodium which cause malaria.
Pregnancy-associated malaria (PAM) or placental malaria is a presentation of the common illness that is particularly life-threatening to both mother and developing fetus. [1] PAM is caused primarily by infection with Plasmodium falciparum , [ 1 ] [ 2 ] the most dangerous of the four species of malaria-causing parasites that infect humans. [ 3 ]
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