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2. 7-Methylxanthine - Wikipedia

   en.wikipedia.org/wiki/7-methylxanthine

   7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine). [1] [2] It is a non-selective antagonist of the adenosine receptors. [1] [2] The compound may slow the progression of myopia (nearsightedness). [1] [2] It is under investigation for this ...

3. Caffeine - Wikipedia

   en.wikipedia.org/wiki/Caffeine

   1,3,7-Trimethyluric acid is a minor caffeine metabolite. [5] 7-Methylxanthine is also a metabolite of caffeine. [194] [195] Each of the above metabolites is further metabolized and then excreted in the urine. Caffeine can accumulate in individuals with severe liver disease, increasing its half-life. [196]

4. 1,3,7-Trimethyluric acid - Wikipedia

   en.wikipedia.org/wiki/1,3,7-Trimethyluric_acid

   Infobox references. 1,3,7-Trimethyluric acid, also referred to as trimethyluric acid and 8-oxy-caffeine, is a purine alkaloid that is produced in some plants and occurs as a minor metabolite of caffeine in humans. [ 1] The enzymes that metabolize caffeine into 1,3,7-trimethyluric acid in humans include CYP1A2, CYP2E1, CYP2C8, CYP2C9, and CYP3A4 ...

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7. Coffee bean - Wikipedia

   en.wikipedia.org/wiki/Coffee_bean

   Caffeine (1,3,7-trimethylxanthine) is the alkaloid most present in green and roasted coffee beans. The content of caffeine is between 1.0% and 2.5% by weight of dry green coffee beans. The content of caffeine does not change during maturation of green coffee beans, but higher caffeine content is found in plants grown at higher altitudes.