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  2. DNA polymerase - Wikipedia

    en.wikipedia.org/wiki/DNA_polymerase

    A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA. These enzymes are essential for DNA replication and usually work in groups to create two identical DNA duplexes from a single original DNA duplex. During this process, DNA polymerase ...

  3. DNA polymerase II - Wikipedia

    en.wikipedia.org/wiki/DNA_polymerase_II

    DNA Polymerase II. (str. K-12 substr. MG1655) DNA polymerase II (also known as DNA Pol II or Pol II) is a prokaryotic DNA-dependent DNA polymerase encoded by the PolB gene. [ 1] DNA Polymerase II is an 89.9-kDa protein and is a member of the B family of DNA polymerases. It was originally isolated by Thomas Kornberg in 1970, and characterized ...

  4. RNA polymerase II - Wikipedia

    en.wikipedia.org/wiki/RNA_polymerase_II

    RNA polymerase II ( RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA (snRNA) and microRNA. [ 1][ 2] It is one of the three RNAP enzymes found in the nucleus of eukaryotic cells. [ 3] A 550 kDa complex of 12 subunits, RNAP II is the most studied type of RNA ...

  5. RNA polymerase - Wikipedia

    en.wikipedia.org/wiki/RNA_polymerase

    RNA polymerase (purple) unwinding the DNA double helix. It uses one strand (darker orange) as a template to create the single-stranded messenger RNA (green). In molecular biology, RNA polymerase (abbreviated RNAP or RNApol ), or more specifically DNA-directed/dependent RNA polymerase ( DdRP ), is an enzyme that catalyzes the chemical reactions ...

  6. RNA polymerase II holoenzyme - Wikipedia

    en.wikipedia.org/wiki/RNA_polymerase_II_holoenzyme

    RNA polymerase II (also called RNAP II and Pol II) is an enzyme found in eukaryotic cells. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA . [3] [4] In humans, RNAP II consists of seventeen protein molecules (gene products encoded by POLR2A-L, where the proteins synthesized from POLR2C , POLR2E ...

  7. DNA polymerase I - Wikipedia

    en.wikipedia.org/wiki/DNA_polymerase_I

    Swiss-model. Domains. InterPro. DNA polymerase I (or Pol I) is an enzyme that participates in the process of prokaryotic DNA replication. Discovered by Arthur Kornberg in 1956, [ 1] it was the first known DNA polymerase (and the first known of any kind of polymerase ). It was initially characterized in E. coli and is ubiquitous in prokaryotes.

  8. DNA synthesis - Wikipedia

    en.wikipedia.org/wiki/DNA_synthesis

    DNA synthesis is the natural or artificial creation of deoxyribonucleic acid (DNA) molecules. DNA is a macromolecule made up of nucleotide units, which are linked by covalent bonds and hydrogen bonds, in a repeating structure. DNA synthesis occurs when these nucleotide units are joined to form DNA; this can occur artificially ( in vitro) or ...

  9. Polymerase - Wikipedia

    en.wikipedia.org/wiki/Polymerase

    Polymerase. In biochemistry, a polymerase is an enzyme ( EC 2.7.7.6/7/19/48/49) that synthesizes long chains of polymers or nucleic acids. DNA polymerase and RNA polymerase are used to assemble DNA and RNA molecules, respectively, by copying a DNA template strand using base-pairing interactions or RNA by half ladder replication. A DNA ...