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Diabetes mellitus type 1 is a disease caused by the lack of insulin. Thus, Insulin is the main treatment agent for type 1 and is typically administered via subcutaneous injection. Diabetes mellitus type 2 is a disease of insulin resistance by cells. Type 2 diabetes mellitus is the most common type of diabetes.
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Type 2 diabetes makes up about 90% of cases of diabetes, with the other 10% due primarily to type 1 diabetes and gestational diabetes. [1] In type 1 diabetes, there is a lower total level of insulin to control blood glucose, due to an autoimmune induced loss of insulin-producing beta cells in the pancreas.
GLP-1 receptor agonist: Approved for type 2 diabetes 2.5 kilograms (5.5 lb) [77] Cetilistat: Absorption inhibitor Not approved 1.5 kilograms (3.3 lb) [78] Tesofensine (NS2330) Serotonin–norepinephrine–dopamine reuptake inhibitor: Not FDA approved 10.6 percent [79] Metformin: Glucophage Unknown Approved for type 2 diabetes 5.6 percent [80 ...
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SGLT2 inhibitors are used in the treatment of type 2 diabetes. Apart from blood sugar control, gliflozins have been shown to provide significant cardiovascular benefit in people with type 2 diabetes. [2] [3] As of 2014, several medications of this class had been approved or were under development. [4]
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