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Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [4] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [3] [5] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [2]
[4] [8] In 1990 there were 10 specialty drugs on the market, [9] around five years later nearly 30, [10] by 2008 200, [10] and by 2015 300. [11] Drugs can be defined as specialty because of their high price. [3] [4] [5] Medicare defines any drug with a negotiated price of $670 per month or more as a specialty drug. These drugs are placed in a ...
With no buyer found after a week, Z Gallerie proceeded to kick off liquidation sales at the remaining 21 locations. [314] Zellers, once a widespread and popular Canadian department store chain, sold its retail leases to Target Canada, which, by 2013, shuttered its Canadian stores. [315] The last two remaining Zellers stores closed on January 26 ...
RetailMeNot, Inc. RetailMeNot, Inc. (formerly Whaleshark Media) is an American multinational company headquartered in Austin, Texas, that maintains a collection of coupon web sites. The company was founded by Cotter Cunningham. [3] The company owns RetailMeNot.com and VoucherCodes.co.uk and acquires coupon sites and third-party software.
It also maintains List I of chemicals and List II of chemicals, which contain chemicals that are used to manufacture the controlled substances/illicit drugs. The list is designated within the Controlled Substances Act [1] but can be modified by the U.S. Attorney General as illegal manufacturing practices change.
Cannabis flowers next to a plastic canister of 3.5 grams. Cannabis in Canada is legal for both recreational and medicinal purposes. Medicinal use of cannabis was legalized nationwide under conditions outlined in the Marihuana for Medical Purposes Regulations, later superseded by the Access to Cannabis for Medical Purposes Regulations, [1] issued by Health Canada and seed, grain, and fibre ...
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