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The partition coefficient, abbreviated P, is defined as a particular ratio of the concentrations of a solute between the two solvents (a biphase of liquid phases), specifically for un- ionized solutes, and the logarithm of the ratio is thus log P. [10] : 275ff When one of the solvents is water and the other is a non-polar solvent, then the log ...
In mathematics, the logarithm is the inverse function to exponentiation. That means that the logarithm of a number x to the base b is the exponent to which b must be raised to produce x. For example, since 1000 = 103, the logarithm base of 1000 is 3, or log10 (1000) = 3.
Druglikeness. Druglikeness is a qualitative concept used in drug design for how "druglike" a substance is with respect to factors like bioavailability. It is estimated from the molecular structure before the substance is even synthesized and tested. A druglike molecule has properties such as:
Lipophilic efficiency [1] ( LiPE ), sometimes referred to as ligand-lipophilicity efficiency ( LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness. [2] [3] For a given compound LiPE is defined as the pIC 50 (or pEC 50 ...
Binary logarithm. Graph of log2 x as a function of a positive real number x. In mathematics, the binary logarithm ( log2 n) is the power to which the number 2 must be raised to obtain the value n. That is, for any real number x , For example, the binary logarithm of 1 is 0, the binary logarithm of 2 is 1, the binary logarithm of 4 is 2, and the ...
Lincoln Logs are an American children's construction toy consisting of square-notched miniature lightweight logs used to build small forts and buildings. They were invented around 1916 by John Lloyd Wright, second son of well-known architect Frank Lloyd Wright. [1] Lincoln Logs were inducted into the National Toy Hall of Fame in 1999.
LogP. LogP may refer to: Partition coefficient, the name of a ratio in organic and medicinal chemistry. LogP machine, a model for parallel computation. Category: Disambiguation pages.
Big Log. " Big Log " is a song by English recording artist Robert Plant. The first single from his second solo studio album, The Principle of Moments (1983), it became his first top 40 solo hit, peaking at No. 11 on the UK Singles Chart and No. 20 on the US Billboard Hot 100. The song also reached No. 6 on the Billboard Top Tracks chart.