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Chemistry [ edit] Fulvestrant, also known as 7α- [9- [ (4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estradiol, is a synthetic estrane steroid and a derivative of estradiol. An alkyl - sulfinyl moiety was added to the endogenous estrogen receptor ligand. [6] It was discovered through rational drug design, but was selected for further development ...
Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor medication that is used in the treatment of breast cancer. [1] It was patented in 1986 and approved for medical use in 1996. [4] In 2021, it was the 222nd most commonly prescribed medication in the United States, with more than 1 million prescriptions.
The combination of a lower dosage of megestrol acetate (40–80 mg/day) and a low oral dosage of an estrogen such as estradiol (0.5–1.5 mg/day), diethylstilbestrol (0.1–0.2 mg/day) or ethinylestradiol (50 μg/day) is able to suppress testosterone levels into the castrate range in men, maintain this suppression long-term, and achieve ...
Hydroxyprogesterone caproate, sold under the brand name Delalutin among others, is a medication used to reduce the risk of preterm birth in women pregnant with one baby who have a history of spontaneous preterm birth. [10] In March 2023, the manufacturer, Covis Pharma, agreed to withdraw the drug from the US market.
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UnitedHealth says files with personal information that could cover a “substantial portion of people in America” may have been taken in the cyberattack earlier this year on its Change ...
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