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In 1944 Howard Florey and Ernst Boris Chain mass-produced penicillin. In 1948 Raymond P. Ahlquist published his seminal work where divided adrenoceptors into α- and β-adrenoceptor subtypes, this allowed a better understanding of drugs mechanisms of action . In 1987, after Montreal Protocol, CFC inhalers were phased out and HFA inhalers ...
Before the 1906 Pure Food and Drug Act, most food oversight was mandated to state laws, which were enacted during the colonial days and served mainly trade interests. [1] They set standards of weight, and "provided for inspections of exports like salt meats, fish and flour". [1] In 1848, the first national law concerned with regulating food ...
2 Pre-20th century. 3 20th century. 4 21st century. Toggle 21st century subsection. 4.1 2020. ... is the first biotech drug to be approved by the Food and Drug ...
The history of the FDA can be traced to the latter part of the 19th century and the U.S. Department of Agriculture's Division of Chemistry (later Bureau of Chemistry). Under Harvey Washington Wiley, appointed chief chemist in 1883, the Division began conducting research into the adulteration and misbranding of food and drugs on the American market.
The Pure Food and Drug Act of 1906, also known as the Wiley Act and Dr. Wiley 's Law, was the first of a series of significant consumer protection laws enacted by the United States Congress, and led to the creation of the Food and Drug Administration (FDA). Its main purpose was to ban foreign and interstate traffic in adulterated or mislabeled ...
The earliest patent medicines were created in the 17th century. They were most popular from the mid-19th century to the early 20th century, before the advent of consumer protection laws and evidence-based medicine. [1] [2] Despite the name, patent medicines were usually trademarked but not actually patented, in order to keep their formulas ...
The first "drugstores" in North America "appeared in Bethlehem, Pennsylvania, Boston, New York, and Philadelphia," [11] with likely proto-drugstores—for example Gysbert van Imbroch ran a "general store" that sold drugs from 1663 to 1665 in Wildwyck, New Netherland, [12] today's Kingston, New York—preceding the dedicated apothecary shops of the 1700s, and providing a model.
In 1910, Ehrlich and Hata announced their discovery, which they called drug "606", at the Congress for Internal Medicine at Wiesbaden. [134] The Hoechst company began to market the compound toward the end of 1910 under the name Salvarsan, now known as arsphenamine. [134] The drug was used to treat syphilis in the first half of the 20th century.