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In the United States, type 1 and 2 diabetes affected about 208,000 youths under the age of 20 in 2015. Over 18,000 youths are diagnosed with Type 1 diabetes every year. Every year about 234,051 Americans die due to diabetes (type I or II) or diabetes-related complications, with 69,071 having it as the primary cause of death. [109]
This is when a type 1 diabetic becomes insulin resistant, the hallmark for type 2 diabetes or has a family history for type 2 diabetes. [73] It was first discovered in 1990 or 1991. The following is a list of disorders that may increase the risk of diabetes: [ 74 ]
Type 2 diabetes makes up about 90% of cases of diabetes, with the other 10% due primarily to type 1 diabetes and gestational diabetes. [1] In type 1 diabetes , there is a lower total level of insulin to control blood glucose, due to an autoimmune induced loss of insulin-producing beta cells in the pancreas .
Type 2 diabetes is a complex condition, and research is ongoing about why the condition develops. Researchers are interested in understanding how the gut microbiome affects type 2 diabetes.
The study included 374,021 veterans with diabetes, with an average age of 73.2 years, and 99% were male. Over a follow-up period of up to 10 years, 11% (41,424) developed ADRD.
Demonstration that intensive glycemic control in type 1 diabetes reduces chronic side effects more as glucose levels approach 'normal' in a large longitudinal study, [149] and also in type 2 diabetics in other large studies; Identification of the first thiazolidinedione as an effective insulin sensitizer during the 1990s
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