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D014807. Legal status. In Wikidata. Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and for many other biological effects. [1] [2] In humans, the most important compounds in this group are vitamin D 3 ( cholecalciferol) and vitamin D 2 ( ergocalciferol ).
Ergocalciferol, also known as vitamin D2 and nonspecifically calciferol, is a type of vitamin D found in food and used as a dietary supplement. [3] As a supplement it is used to prevent and treat vitamin D deficiency. [4] This includes vitamin D deficiency due to poor absorption by the intestines or liver disease. [5]
Calcitriol. Calcitriol is the active form of vitamin D, normally made in the kidney. [8] [9] [10] It is also known as 1,25-dihydroxycholecalciferol. It is a hormone which binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes. [11]
Cholecalciferol is a form of vitamin D which is naturally synthesized in skin and functions as a pro-hormone, being converted to calcitriol. This is important for maintaining calcium levels and promoting bone health and development. [4] As a medication, cholecalciferol may be taken as a dietary supplement to prevent or to treat vitamin D ...
Vitamin D deficiency is a concern for infants, especially in the Northern Hemisphere. This is because infants often have very limited exposure to sunlight, which is the main source of endogenous Vitamin D production. Vitamin D deficiency can result in rickets, a disease in which bones become soft and pliable. Vitamin E is a potent anti-oxidant ...
22-Dihydroergocalciferol is a form of vitamin D, also known as vitamin D 4. It has the systematic name (5Z,7E)-(3S)-9,10-seco-5,7,10(19)-ergostatrien-3-ol. Vitamin D 4 is found in certain mushrooms, being produced from ergosta-5,7-dienol (22,23-dihydroergosterol) instead of ergosterol. See also
Vitamin D is a steroid hormone that plays a vital role in calcium and phosphate absorption. Recent studies show several associations between low levels of vitamin D, or hypovitaminosis D, and neuropsychiatric disorders, [1] including Alzheimer's disease, autism, epilepsy, multiple sclerosis, Parkinson's disease, and schizophrenia. [1] [2]
Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body. [1] [7] [2] One nanogram per millilitre ( 1 ng/mL) is equivalent to 2.5 nanomoles per litre ( 2.5 nmol/L ). Severe deficiency: < 12 ng/mL = < 30 nmol/L [2 ...