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Bupropion was originally called by the generic name amfebutamone, before being renamed in 2000. [ 16 ] In 2022, it was the 21st most commonly prescribed medication in the United States, with more than 25 million prescriptions. [ 38 ][ 39 ] It is on the World Health Organization's List of Essential Medicines.
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Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [ 4 ] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [ 3 ][ 5 ] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [ 2 ] Reintroduced 2002 with restricted indication ...
The economist Alex Tabarrok has argued, that the success of this promotion lies in the fact that consumers value the first unit significantly more than the second one. So compared to a seemingly equivalent "Half price off" promotion, they may only buy one item at half price, because the value they attach to the second unit is lower than even the discounted price.
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Trazodone, sold under many brand names, [ 1 ] is an antidepressant medication, [ 20 ] used to treat major depressive disorder, anxiety disorders, and insomnia. [ 20 ] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class. [ 21 ][ 22 ] The medication is taken orally.
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