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Trazodone, sold under many brand names, [1] is an antidepressant medication. [20] It is used to treat major depressive disorder, anxiety disorders, and insomnia. [20] The medication is taken orally. [20] Common side effects include dry mouth, feeling faint, vomiting, and headache. [20]
Death can occur from overdosing on a single or multiple drugs, or from combined drug intoxication (CDI) due to poly drug use. Poly drug use often carries more risk than use of a single drug, due to an increase in side effects, and drug synergy .
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A 2006 review suggests that the widespread use of antidepressants in the new "SSRI-era" appears to have led to a highly significant decline in suicide rates in most countries with traditionally high baseline suicide rates. The decline is particularly striking for women who, compared with men, seek more help for depression.
They found 37 deaths by suicide in the antidepressant group (31.781 patients), and only 4 deaths by suicide in the placebo group (10.080 patients). Apart from this the rates of suicide attempts were 2.5 times higher in the people taking antidepressants than in those who were given the placebo: 206 suicide attempts in people taking ...
The randy research, recently published in the Journal of Psychosexual Health, found that females aged 20 to 59 who had sex infrequently — less than once per week — were at a 70% increased risk ...
A 2000 global study on homicide by the United Nations Office on Drugs and Crime found that men account "for an average of 95 per cent of all persons convicted of homicide in 53 countries" [1] and 79% of the victims (see the chart below). The highest female homicide rate per 100,000 inhabitants was in Honduras and highest male homicide rate per ...
Alcohol, heroin, and prescription opioids, with morphine being the opioid with the highest mortality rate. [56] A 1993 British study found temazepam to have the highest number of deaths per million prescriptions among medications commonly prescribed in the 1980s (11.9, versus 5.9 for benzodiazepines overall, taken with or without alcohol). [57]
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